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- Physiology of breathing
- Complications from respiratory muscle weakness in ALS
- Some questions asked by ALS patients and their caregivers
- Treatment options
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3
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4
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5
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6
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7
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- Hypoventilation/Shortness of breath
- Pneumonia syndromes
- Airway obstruction
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8
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- Hypoventilation syndrome
- Breathlessness
- Inability to cough and clear secretions
- Diminished voice volume
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- Shortness of breath when walking or during rest
- Inability to lie flat in bed
- Poor strength of cough
- Inability to clear secretions from the throat and lungs
- Increased salivary secretions
- Recurrent chest infections and pneumonia
- Respiratory failure (high blood carbon dioxide level)
- Poor sleep
- Fatigue
- Headache
- Anxiety, panic episodes
- Anorexia, unexpected weight loss
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10
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- Why do I feel short of breath when I lie down ?
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11
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- Clinical
- Spirometry (FVC, MIP, MEP, MVV)
- Nocturnal pulse oxymetry
- Arterial blood gas
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12
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- What can be done about weakening respiratory muscles?
- Optimal nutrition
- Adequate rest
- Prevention of aspiration
- Prevention of infection (Flu shot, Pneumovaccine)
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13
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14
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- What I do when my weak muscles fail to produce an effective cough ?
- Assist cough
- Cough machine (insufflation/exsufflation)
- Postural drainage
- Tracheostomy
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15
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16
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17
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- 1. No mechanical support
- 2. Non invasive ventilation
- 3. Tracheostomy and mechanical ventilatory support
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18
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19
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20
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- Which option is best for me?
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21
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