Help us to determine the safety and efficacy of an experimental drug

Recruiting patients with SOD1 ALS

Study Name
Biogen SOD1 Clinical Trial
PI
Michael Benatar, MD, PhD
Study Type
Interventional (Clinical Trial). Phase III. Randomized. Placebo-controlled
Eligible Population

Individuals affected with ALS, and positive for an SOD1 gene mutation that is associated with rapidly progressive disease

Study Purpose/Goals

To determine the safety and efficacy of the experimental drug BIIB067 in patients with SOD1 ALS

Procedures/Participation
  • 40 weeks of participation
  • Screening: up to 7 weeks
  • Treatment: 28 weeks (5 doses, once every 2 weeks x 2 doses, then once every 4 weeks
  • Follow-up: 32 weeks
  • Open label extension

Procedures

  • Medical history and medication review
  • Drug dosing
  • Blood, urine and CSF collection
  • Neurological exam
  • Muscle testing
  • Electrocardiogram
  • Physical exam
  • Surveys
  • Breathing tests
  • Biomarker procedures (EIM, HHD, MUNIX)

Join our family - together, we can change the course of this disease.

Join our family

Together, we can change the course of this disease.

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